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特发性血小板减少性紫癜(ITP)时血小板膜上的免疫球蛋白G(IgG)增高,但对ITP的骨髓巨核细胞上的抗体了解甚少。本文目的是研究儿童ITP骨髓巨核细胞膜上抗体。共观察61例,其中32例在急性期检查的,29例在缓解期检查的。32例中12例未经特殊治疗,20例经激素治疗。对照组是11例健康儿童。骨髓巨核细胞是通过胸骨穿刺而得,巨核细胞膜上免疫球蛋白是采用免疫荧光法测得。在ITP急性期不论是否接受激素治疗,其骨髓中的巨核细胞绝对数和相对数比对照组皆多2倍以上。而
ITP increases platelet membrane immunoglobulin G (IgG) but little is known about antibodies on ITP’s bone marrow megakaryocytes. The purpose of this paper is to study the membrane-bound antibodies to ITP bone marrow megakaryocytes in children. A total of 61 cases were observed, of which 32 cases were examined in the acute phase and 29 cases were examined in the remission. Twelve of 32 patients were untreated and 20 were treated with steroid. The control group was 11 healthy children. Bone marrow megakaryocytes are obtained through the sternal puncture, megakaryocytic membrane immunoglobulin is measured by immunofluorescence. In the acute phase of ITP, whether in hormone therapy or not, the absolute number and the relative number of megakaryocytes in the bone marrow were more than 2 times more than those in the control group. and