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10-羟基癸烯酸(10-HDA)抑制应激、结扎幽门和消炎痛性胃溃疡的形成.促进醋酸性胃溃疡的愈合。并且能抑制胃酸分泌.具有剂量依赖关系,促进胃壁结合粘液.胃组织DNA、cAMP和胃粘膜前列腺素E2含量增加.提示.10-HDA抗胃溃疡作用可能与其抑制胃酸分泌及增强胃粘膜细胞保护作用有关。
10-Hydroxydecanoic acid (10-HDA) inhibits stress, ligation of pylorus and indomethacin-induced gastric ulcer formation. Promote the healing of acetic acid ulcer. And can inhibit gastric acid secretion. A dose-dependent manner, to promote gastric mucus. Gastric tissue DNA, cAMP and gastric mucosa prostaglandin E2 content increased. prompt. The anti-gastric ulcer effect of 10-HDA may be related to its inhibition of gastric acid secretion and enhancement of gastric mucosal cell protection.