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〔目的〕探讨99mTc-甲氧基异丁基异睛（MIBI）对鉴别甲状腺冷（凉）结节良恶性的临床价值。[方法］对61例99mTc-高锝酸钠（99mTcO4－）显像为冷（凉）结节的患者行99mTc-MIBI显像，〔结果〕61例全部经手术切除，获得病理结果。61例中17例为甲状腺癌，99mTc－MIBI显像15例阳性，其中6例有淋巴结转移者淋巴结均呈阳性；另外44例为甲状腺良性病变，8例假阳性。诊断的灵敏度、特异性和假阳性率分别为88.24％（15／17）、81.82％（36／44）和18.18％（8／44）。［结论］99mTc－MIBI显像对鉴别甲状腺冷（凉）给节的良恶性具有重要的临床应用价值。
[Objective] To investigate the clinical value of 99mTc-methoxyisobutylisothiazide (MIBI) in the differentiation of benign and malignant thyroid cold (cold) nodules. [Methods] 99mTc-MIBI imaging was performed on 61 patients with 99mTc-sodium pertechnetate (99mTcO4-) imaging as cold (cold) nodules. All 61 cases were surgically resected to obtain pathological results. Of the 61 patients, 17 were thyroid cancers, and 99mTc-MIBI imaging was positive in 15 cases. Lymph node metastases were positive in 6 cases with lymph node metastases; 44 cases were benign thyroid diseases and 8 were false-positive. The sensitivity, specificity and false positive rate of diagnosis were 88.24% (15/17), 81.82% (36/44) and 18.18% (8/44), respectively. [Conclusion] 99mTc-MIBI imaging has important clinical application value in differentiating benign and malignant thyroid cold (cold) sections.