论文部分内容阅读
目的:研究四肢恶性骨肿瘤保肢手术前经导管动脉栓塞化疗(Transcatheterarteritalchemobolization,TACE)的临床应用价值。方法:回顾性分析经手术及病理证实的12例骨肉瘤,分别采用了碘油悬浊液及明胶海绵行超选择性动脉栓塞化疗;术后平均2～6天进行保肢手术。结果:经介入治疗后的全部病例有11例瘤体被完全切除并保留肢体,7例疼痛症状明显减轻;3例疼痛症状基本消失;全部病例均有不同程度的功能改善,软组织肿块变小或消失,术中大大减少了出血量。介入后肿瘤染色及碘油沉积与病理坏死结果显示一致,4例显示轻中度坏死(20%～60%);7例显示重度坏死(60%～100%)。结论:经导管动脉内栓塞化疗术是四肢骨肉瘤保肢术前的一种十分有效的方法,值得应用推广。
Objective: To study the clinical value of transcatheter arterial chemoembolization (TACE) before salvage limb salvage surgery. Methods: A retrospective analysis of 12 cases of osteosarcoma confirmed by surgery and pathology were performed with lipiodol suspension and gelatin sponge in the treatment of superselective arterial embolization. On average, limb salvage surgery was performed 2-6 days after operation. Results: In all the cases after the interventional treatment, 11 cases of the tumor were completely resected and the limbs were preserved, the pain symptoms of 7 cases were alleviated obviously. The pain symptoms disappeared in 3 cases. All cases had different degrees of functional improvement, the soft tissue mass became smaller or Disappear, intraoperative greatly reduced the amount of bleeding. After intervention, tumor staining and lipiodol deposition were consistent with pathological necrosis findings. Four cases showed mild to moderate necrosis (20% -60%) and seven cases showed severe necrosis (60% -100%). Conclusion: Transcatheter arterial chemoembolization is a very effective method for limb salvage of extremities osteosarcoma before limb salvage. It is worth to be popularized.