论文部分内容阅读
目的探讨生长抑素在急性粘连性肠梗阻治疗中的临床应用和疗效。方法将急性粘连性肠梗阻患者80例机分为常规治疗组和生长抑素治疗组各40例,2组患者入院时均采用非手术治疗,生长抑素治疗组在常规治疗基础上加用生长抑素(250μg/h持续静脉滴注2～5d)。2组患者治疗过程中出现手术指征则立即手术。结果生长抑素治疗组与常规治疗组相比,腹痛、腹胀缓解时间缩短〔(2.7±0.9)dvs(3.9±1.1)d,P<0.05〕,肛门排气时间提前〔(3.60±0.77)dvs(5.30±0.97)d,P<0.05〕,胃肠减压引流量减少〔(424.75±55.52)ml/dvs(602.95±108.07)ml/d,P<0.05〕,手术比率减低〔12.5%vs45.0%,P<0.05〕,平均住院日缩短〔(7.3±1.3)dvs(10.3±2.0)d,P<0.05〕。结论在常规治疗基础上加用生长抑素治疗急性粘连性肠梗阻可有效缓解症状,减少患者手术的比率,缩短平均住院日。
Objective To investigate the clinical application and effect of somatostatin in the treatment of acute adhesive intestinal obstruction. Methods Eighty patients with acute adhesive intestinal obstruction were divided into routine treatment group and somatostatin treatment group, 40 cases in each group. Non-surgical treatment was used in both groups. The somatostatin treatment group was given routine treatment (250μg / h continuous intravenous infusion of 2 ~ 5d). Two groups of patients with surgical indications during surgery immediately surgery. Results Compared with the conventional treatment group, the time to relieve abdominal pain and abdominal distension in the somatostatin treatment group was shorter than that in the conventional treatment group 〔(2.7 ± 0.9) d vs (3.9 ± 1.1) d, P <0.05〕, and the anal exhaust time was earlier (3.60 ± 0.77) dvs (5.30 ± 0.97) d, P <0.05〕. The reduction of gastrointestinal decompression and drainage was (424.75 ± 55.52) ml / d vs (602.95 ± 108.07) ml / d, 0%, P <0.05). The mean length of stay was shorter (7.3 ± 1.3) d vs (10.3 ± 2.0) days, P <0.05. Conclusion The combination of somatostatin and conventional treatment of acute adhesive intestinal obstruction can effectively relieve the symptoms, reduce the rate of operation of patients and shorten the average length of stay.