CT小肠造影评估Crohn's病活动度的临床价值

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目的探讨计算机断层扫描(CT)小肠造影评估Crohn’s病活动度的临床价值。方法 42例活动期Crohn’s病患者作为观察组,33例缓解期Crohn’s病患者作为对照组。所有患者均接受CT小肠造影检查,对比检查结果。结果两组患者的病变强化方式比较,差异有统计学意义(P<0.05)。观察组肠腔狭窄或梗阻例数多于对照组,游离缘假性憩室例数少于对照组,差异均具有统计学意义(P<0.05)。观察组肠系膜密度增高、腹腔淋巴结肿大、梳状征、蜂窝织炎例数均多于对照组,差异均具有统计学意义(P<0.05)。观察组肠壁厚度为(10.6±2.5)mm,厚于对照组的(4.9±2.0)mm,观察组病变肠壁动脉期CT值为(97.1±13.5)Hu、病变肠壁门脉期CT值为(109.8±14.6)Hu,均高于对照组的(74.2±6.4)、(81.6±5.7)Hu,差异均具有统计学意义(P<0.05)。结论 CT小肠造影可以准确地鉴别Crohn’s病活动期与缓解期,在评估Crohn’s病活动度方面有重要的临床实用价值。 Objective To investigate the clinical value of computed tomography (CT) small bowel angiography in assessing the activity of Crohn’s disease. Methods 42 cases of active Crohn’s disease patients as the observation group and 33 patients with Crohn’s disease during the remission as the control group. All patients underwent CT small bowel examination contrasting the results. Results The two groups of patients with lesion enhancement methods, the difference was statistically significant (P <0.05). The number of intestinal stenosis or obstruction in the observation group was more than that of the control group, and the number of pseudo-diverticulum with free edge was less than that of the control group (P <0.05). In observation group, the mesenteric density increased, abdominal lymph nodes, combs and cellulitis were more in the observation group than in the control group, with significant differences (P <0.05). The thickness of the intestinal wall in the observation group was (10.6 ± 2.5) mm, which was thicker than that in the control group (4.9 ± 2.0) mm. The CT value of the arterial phase in the observation group was (97.1 ± 13.5) (109.8 ± 14.6) Hu were higher than those in the control group (74.2 ± 6.4) and (81.6 ± 5.7) Hu, respectively. The differences were statistically significant (P <0.05). Conclusion CT small bowel angiography can accurately identify Crohn’s disease activity and remission, in the evaluation of Crohn’s disease activity has an important clinical value.
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