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用复方多烯磷脂酰胆碱软胶囊及安慰剂按随机双盲方式对慢性乙型活动性肝炎成年病人作了疗效观察.治疗时间为6个月.在所观察的16项生化项目中,治疗结束时,仅谷丙转氨酶及谷草转氨酶在两组之间有统计学上的显著性差异:复方多烯磷脂酰胆碱组比安慰剂组有显著降低;在乙肝病毒标志方面.HBeAg及抗-HBe IgM两项复制标志转阴的例数,在复方多烯磷脂酰胆碱组比较多些;自觉症状在复方多烯磷脂酰胆碱组也比安慰剂组较多明显的改善;全部病例都能很好耐受药物治疗而无明显副作用.总的评估:复方多烯磷脂酰胆碱组的治疗成功率比安慰剂组显著为高.
With compound polyene phosphatidylcholine soft capsules and placebo in a randomized double-blind manner for chronic hepatitis B patients with adult efficacy was observed. The treatment time was 6 months in the observed 16 biochemical projects, treatment At the end of the day, only alanine aminotransferase and aspartate aminotransferase had a statistically significant difference between the two groups: the compound polyene phosphatidylcholine group was significantly lower than the placebo group; in the case of hepatitis B virus markers, HBeAg and anti- HBe IgM two copies of the negative sign of replication markers in the compound polyene phosphatidylcholine group more; subjective symptoms in the compound polyene phosphatidylcholine group also significantly improved more than the placebo group; all cases Well-tolerated drug treatment without significant side effects Overall assessment: The compound polyene phosphatidylcholine group had a significantly higher success rate than the placebo group.