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目的:比较布托啡诺与芬太尼复合丙泊酚对人工流产手术的麻醉效果。方法选择100例自愿终止妊娠的早孕妇女,随机分为两组,每组50例。B组为布托啡诺组:先静注布托啡诺20μg/kg,待患者消毒铺巾后再静注丙泊酚2.0mg/kg;F组为芬太尼组:先静注芬太尼1.0μg/kg,待患者消毒铺巾后再静注丙泊酚2.0mg/kg。术中根据患者反应酌情追加丙泊酚。结果:两组患者均较好地完成手术,两组患者术中丙泊酚的用量、体动、注射痛、苏醒时间、术后宫缩痛等无明显差异;F组呼吸抑制明显多于B组(P<0.05),宜F组有三例病人术后出现恶心呕吐现象,而B组未观察到有恶心呕吐的病人。结论布托啡诺与芬太尼复合丙泊酚均可用于无痛人流手术,而布托啡诺引起的呼吸抑制明显少于芬太尼,几乎无副作用,值得在临床推广应用。
Objective: To compare the anesthetic effects of butorphanol and fentanyl combined with propofol on induced abortion. Methods 100 pregnant women with voluntary termination of pregnancy were randomly divided into two groups of 50 cases each. B group of butorphanol group: the first intravenous injection of butorphanol 20μg / kg, patients were disinfected and then intravenous infusion of propofol 2.0mg / kg; F group of fentanyl group: the first intravenous injection of fen Ni 1.0μg / kg, until the patient disinfection shop towel intravenous infusion of propofol 2.0mg / kg. Surgery based on patient response, as appropriate, additional propofol. Results: The two groups of patients completed the surgery well. There was no significant difference in propofol dosage, body movement, injection pain, recovery time and postoperative uterine contraction between the two groups. Respiratory depression in group F was significantly more than that in group B Group (P <0.05), three patients in group F should have nausea and vomiting after operation, but no patients in group B had nausea and vomiting. Conclusion Butorphanol and fentanyl combined with propofol can be used for painless abortion, but the butorphanol caused respiratory depression was significantly less than fentanyl, almost no side effects, it is worth in the clinical application.