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本文报告对２５８ 名小学生应用０、１、６ 月程序，接种２ 批国产酵母疫苗（５ μｇ／０．５ ｍ ｌ），１ 批Ａｍ ｇｅｎ 酵母疫苗（１０ μｇ／ｍ ｌ），１ 批Ｍ ＳＤ 酵母疫苗（５ μｇ／０．５ ｍ ｌ）的小学生免后３ 年（（Ｔ３６）效果观察。结果表明，Ｔ３６ 时抗体 ＧＭＴ（几何平均滴度），Ａｍ ｇｅｎ 疫苗组（１４５．７５）显著高于 ２ 批国产疫苗（９２．１１、８３．５２）和Ｍ．Ｓ．Ｄ 苗组（７４．６２），抗体ＧＭＴ 峰值显著低于Ａｍ ｇｅｎ 和Ｍ ．Ｓ．Ｄ 苗的２ 批国产酵母疫苗，与Ｍ．Ｓ．Ｄ 苗抗体ＧＭＴ 水平无显著差异（Ｐ＞ ０．０５）。抗体阳转率间各疫苗组均无显著差异（９３．１０％ ～７４．１４％ ）。本次随访结果表明，采用０，１，６ 免疫程序，国产酵母疫苗免后３ 年的抗体阳转率和抗体ＧＭＴ水平不低于进口同类酵母疫苗的水平。
Two hundred batches of domestic yeast vaccine (5 μg / 0.5 ml), one batch of Amgen yeast vaccine (10 μg / ml), one batch of M SD The results of three-year (T36) -free post-prandial administration of yeast vaccine (5 μg / 0.5 m l) showed that GMT (geometric mean titer) and Am gen vaccine group (145.75) In the two batches of domestic vaccines (92.11,83.52) and the M.S.D vaccine group (74.62), the peak GMT of antibodies was significantly lower than the two batches of homemade yeast vaccines of Am gen and M.S.D seedlings, There was no significant difference (P> 0.05) between the antibody titer and the MST antibody level of M.S.D vaccine (93.10% ~ 74.14%). The results of this follow-up , 0,1,6 immune program, domestic yeast vaccine-free 3 years after the antibody positive rate and antibody GMT levels Lower than the level of imports of similar yeast vaccine.