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采用全价颗粒饲料喂养,定期定量ip右旋糖酐铁1.0~2.0ml/周(含铁50~100mg/周)的方法建立了高铁对大鼠主要脏器病理损伤的动物模型。取大鼠主要脏器进行标本处理、制作,并在光镜和电镜下观察、拍片。结果表明实验组和对照组有显著差异,实验组大鼠心脏、肝脏组织细胞发生了不同程度的病理损伤。
The animal model of high-speed rail injury to major organs in rats was established by feeding full-price pellet feed and regular quantitative ip iron dextran 1.0 ~ 2.0ml / week (iron 50 ~ 100mg / week) Take the main organs of rats for specimen preparation, production and observation under light and electron microscopy, filming. The results showed that the experimental group and the control group were significantly different, the experimental group of rat heart, liver tissue cells have varying degrees of pathological damage.