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类胰蛋白酶(tryptase)只存在于肥大细胞中。因此。tryptase阳性细胞即可能确定是肥大细胞。近年的研究表明,肥大细胞在一些器官的纤维增生症中有重要作用。为了了解肝硬化患者及正常人肝脾组织中肥大细胞分布,我们用抗人tryptase单克隆抗体对正常人及肝硬化患者肝脾组织进行了免疫组织化学染色,现将结果报
Tryptase is present only in mast cells. therefore. Tryptase positive cells may be identified as mast cells. Recent studies have shown that mast cells play an important role in the pathogenesis of fibrogenesis in some organs. In order to understand the distribution of mast cells in liver and spleen of patients with cirrhosis and normal liver, we used immunohistochemical staining of anti-human tryptase monoclonal antibody to liver and spleen of normal and cirrhosis patients.