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目的调查社区老年人轻度帕金森病样体征的患病率,研究伴有轻度帕金森病样体征(MPS)与轻度认知功能损害(MCI)之间的关系。方法以492例≥60岁老年人为研究对象,使用帕金森病统一评分量表(the unified Parkinson’s disease rating scale,UPDRS)第3部分缩写版本评定MPS。将研究对象分为MPS组和无MPS组,比较MCI患病情况,分析MPS与MCI之间联系。结果 MPS组较无MPS组的年龄大,糖尿病比例、遗忘型MCI(MCI-amnestic,A-MCI)发病率高,差异有统计学意义(P<0.05)。结论 MPS与MCI的发生关系密切,不同类型MPS对MCI影响不同。
Objective To investigate the prevalence of mild Parkinson’s disease-like signs in community elders and to investigate the association between mild Parkinson’s disease-like signs (MPS) and mild cognitive impairment (MCI). Methods 492 elderly people ≥60 years of age were enrolled in this study. MPS was assessed using abbreviated versions of Part 3 of the unified Parkinson’s disease rating scale (UPDRS). Subjects were divided into MPS group and non-MPS group. The prevalence of MCI was compared and the relationship between MPS and MCI was analyzed. Results The MPS group was older than the MPS group. The incidence of diabetes mellitus and MCI-amnestic was the highest in MPS group (P <0.05). Conclusion The occurrence of MPS and MCI are closely related, and different types of MPS have different effects on MCI.