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目的 对健康孕妇进行丙型肝炎病毒 (HCV)感染的危险因素进行研究。方法 对 1995～ 1998年上海市浦南医院 2 783名健康孕妇进行HCV感染的危险因素单因素和多因素分析。结果 人工流产次数及配偶抗 HCV阳性 ,在Logistic回归模型的多因素分析中具有意义。调查中发现 ,待业无工作的孕妇中人工流产史占人工流产者的 71.82 % ,其抗 HCV感染率为 7.37% ,高于其他职业孕妇。本次调查未发现年龄、婚姻、手术、住院、吸毒史等因素与感染HCV有关。结论 人工流产是健康孕妇感染HCV的主要危险因素 ,随着人工流产次数的增加抗HCV的阳性率也增加 ,应加强对人工流产术的仪器灭菌和消毒。
Objective To study the risk factors of hepatitis C virus (HCV) infection in healthy pregnant women. Methods Single factor and multivariate analysis were performed on risk factors of HCV infection in 2 783 healthy pregnant women in Punan Hospital, Shanghai from 1995 to 1998. Results The number of induced abortion and the anti-HCV positive of spouse were significant in multivariate analysis of Logistic regression model. The survey found that pregnant unemployed unemployed pregnant women accounted for 71.82% of induced abortion, the anti-HCV infection rate was 7.37%, higher than other occupational pregnant women. The survey found no age, marriage, surgery, hospitalization, history of drug abuse and other factors associated with HCV infection. Conclusions Induced abortion is a major risk factor for HCV infection in healthy pregnant women. With the increase of the number of induced abortion, the positive rate of anti-HCV is also increasing. Therefore, it is necessary to sterilize and sterilize the equipment for abortion.