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酶类的测定,已在临床上广泛应用,但往往是非特异性的。对心肌疾患血清酶类的改变,据文献报导,磷酸肌酸激酶(CPK)和乳酸脱氢酶(LDH)两者的同工酶已被认为是诊断心肌梗死的特异的最敏感的方法。KJekshus报导CPK释放到血循环中,好似慢慢注射指示剂染料一样,连续测定血清中该酶,绘出曲线,可以计算急性梗死的面积大小。CPK同工酶按其分子中M及B亚基,有三种二聚体同工酶;MM、MB、BB三型。LDH为M及H两种亚基构成四聚体。LDH_1为4个H亚基组成,LDH_2有3个H1个M亚基组成,依次为LDH_3,LDH_4及LDH_5。其活性次序正常为LDH_2>LDH_1>LDH_3>LDH_4>LD
Enzymes determination, has been widely used in clinical practice, but often non-specific. It has been reported in the literature that isozymes of both phosphocreatine creatine kinase (CPK) and lactate dehydrogenase (LDH) have been identified as the most specific and specific method for the diagnosis of myocardial infarction. KJekshus reports that CPK is released into the bloodstream as though slowly injecting the indicator dye, continuously measuring the serum in the enzyme and plotting the curve to calculate the size of the area of the acute infarct. CPK isoenzymes according to their molecules M and B subunits, there are three dimer isoenzymes; MM, MB, BB three types. LDH is composed of M and H two subunits tetramer. LDH_1 consists of 4 H subunits, and LDH_2 consists of 3 H1 M subunits, followed by LDH_3, LDH_4 and LDH_5. The order of its activity was normal LDH_2> LDH_1> LDH_3> LDH_4> LD