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1.用葉酸拮抗劑治療14個急性白血病患者,其中包括6名小兒由11個月至8歲,2個青年患者由15歲至17歲6個成人由26至63歲,其中4例爲急性骨髓性白血病,7名爲急性淋巴白血病,3例爲急性單核細胞性白血病。 2.治療方法用輸血,各種抗生素及葉酸拮抗劑 (Aminopterin及A-methopterin) 若用前者則每日可肌肉注射0.5至2.0兞後者,則每日用2至4兞。 3.由此治療後發生之效果有數種,(a)臨床症狀減輕,血液像上有著明進步,且完全恢復至正常。(b)僅輕度减輕,(c)無效。 4.臨床症狀及血液像完全恢復正常之2例中,1例僅經81天又再發而死亡,1例經30天又再
1. Treatment of 14 acute leukemia patients with folic acid antagonists, including 6 children aged 11 months to 8 years, 2 young patients aged 15 to 17 years 6 adults aged 26 to 63 years, of whom 4 were acute Myeloid leukemia, 7 were acute lymphocytic leukemia and 3 were acute monocytic leukemia. 2. Treatment with blood transfusion, a variety of antibiotics and folic acid antagonists (Aminopterin and A-methopterin) with the former intramuscular injection of 0.5 to 2.0 per day the latter, the daily use of 2 to 4 兞. 3. There are several effects resulting from this treatment, (a) a reduction in clinical symptoms, a clear improvement in the blood picture, and a complete return to normal. (b) mild relief only, (c) invalid. Among the 2 cases with clinical symptoms and complete recovery of blood, 1 patient died again after 81 days and another patient died after 30 days