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目的:比较左、右耳记录的言语诱发听性脑干反应(speech-ABR)在时域及频域上的差异,探讨脑干编码不同耳别来源的言语信息的差异及其可能原因。方法:以合成言语/da/为刺激声对健康成人进行双耳同侧记录的speech-ABR测试,分析反应的潜伏期、幅值及波形评分。对反应20～50ms部分进行快速傅立叶变换,计算基频及第一共振峰的幅值。结果:不同耳别记录的speech-ABR主波的潜伏期差异无统计学意义;右耳记录的A波幅值显著大于左耳记录,O波幅值则显著小于左耳记录,其他主波幅值的耳别差异均无统计学意义。右耳记录的波形评分大于左耳记录,两者差异有统计学意义。无论记录耳别,基频的幅值均大于第一共振峰的幅值,差异有统计学意义;无论是基频的幅值还是第一共振峰的幅值,耳别差异均无统计学意义。结论:speech-ABR在脑干的来源和分布无明显偏向性,与大脑半球言语功能的不对称性无明显对应性。听觉传导通路、功能性what-where通路以及大脑两侧半球不是简单的对应关系。
OBJECTIVE: To compare speech-ABR differences recorded in the left and right ears in the time and frequency domains of speech-induced brainstem response and to explore the differences and possible causes of verbal messages between different ears of brainstem coding. Methods: The speech-ABR test was performed on both sides of healthy adults with synthesized speech / da / stimulus, and the response latency, amplitude and waveform score were analyzed. The response of 20 ~ 50ms part of the Fast Fourier Transform to calculate the amplitude of the fundamental frequency and the first formant. Results: There was no significant difference in the latency of speech-ABR between different ear recordings. The amplitude of A wave in the right ear was significantly larger than that in the left ear, while the amplitude of O wave was significantly lower than that of the left ear. No difference between the ears were not statistically significant. Right ear recorded waveform score greater than left ear record, the difference was statistically significant. Regardless of the recording aural distance, the amplitude of the fundamental frequency is greater than the amplitude of the first formant, the difference was statistically significant; no matter the amplitude of the fundamental frequency or the amplitude of the first formant, the difference was not statistically significant . Conclusion: There is no obvious bias in the origin and distribution of speech-ABR in the brainstem and no significant correspondence with the asymmetry of speech function in the hemisphere of the brain. Auditory conduction pathways, functional what-where pathways, and hemispheres on both sides of the brain are not simply correspondences.