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目的探讨声触诊组织成像量化技术在睾丸良、恶性病变鉴别诊断中的应用价值。方法睾丸良性病变患者31例,恶性病变患者31例,采用声触诊组织成像量化技术检测睾丸病灶内部及正常睾丸剪切波速度(shear wave velocity,SWV),并与同期体检健康者50例(对照组)进行比较。结果睾丸良性病灶内部和恶性病灶内部SWV[(1.12±0.37)、(2.36±0.41)m/s]高于对照组正常睾丸组织[(0.81±0.14)m/s](P<0.05),睾丸恶性病灶内部SWV高于良性病灶(P<0.05);绘制ROC曲线,病灶内部SWV诊断睾丸恶性病变的AUC为0.856,95%CI为0.786~0.947,最佳诊断截点为2.04m/s;与组织病理结果进行对照,病灶内部SWV≥2.04m/s诊断睾丸恶性病变的敏感性为82.6%,特异性为85.4%,准确率为84.8%。结论声触诊组织量化技术可定量评价睾丸病变组织的硬度,在睾丸病变定性诊断中有较高价值。
Objective To explore the value of quantitative imaging of acoustic palpation in the differential diagnosis of benign and malignant testicular lesions. Methods Thirty-one patients with testicular benign disease and 31 patients with malignant lesions were examined with acoustic palpation tissue imaging quantitative technique to detect the shear wave velocity (SWV) in the testes and normal testes, and compared with 50 healthy controls Control group) for comparison. Results The SWV in the testicular benign lesion was significantly higher than that in the normal testes [(1.12 ± 0.37), (2.36 ± 0.41) m / s [(0.81 ± 0.14) m / s] The intracranial SWV in malignant lesions was higher than that in benign lesions (P <0.05). The ROC curve was constructed. The AUC of intracranial SWV in diagnosing testicular malignant lesions was 0.856, the 95% CI was 0.786-0.947, and the best cutoff point was 2.04 m / s. Histopathological results were compared. The sensitivity and specificity of SWV≥2.04m / s in diagnosis of testicular malignant lesions were 82.6%, 85.4% and 84.8% respectively. Conclusion The acoustic palpation tissue quantification technique can quantitatively evaluate the hardness of testicular lesions and has high value in the qualitative diagnosis of testicular lesions.