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目的探索~(14)C尿素呼气试验(UBT)和蛋白芯片抗体(CagA、VacA和Ure)检测诊断Hp感染中的价值。方法 230例患者分别进行~(14)C-UBT和蛋白芯片抗体检测,对结果进行分析。结果 230例患者~(14)C-UBT测定阳性总数100例,阳性率43.4%,~(14)C-UBT阳性患者蛋白芯片抗体阳性总数38例,阳性率38%。230例蛋白芯片抗体阳性总数77例,阳性率33.5%,蛋白芯片抗体阳性患者的~(14)C-UBT阳性数36例,阳性率46.7%。结论本组患者的蛋白芯片抗体、~(14)C呼气试验阳性率低于我国幽门螺旋杆菌平均感染率,说明以上两种方法用于诊断Hp感染的敏感性有待提高。
Objective To explore the value of ~ (14) C urea breath test (UBT) and protein chip antibody (CagA, VacA and Ure) in the diagnosis of Hp infection. Methods 230 patients were detected by ~ (14) C-UBT and protein chip antibody, the results were analyzed. Results The positive rate of C-UBT in 230 patients was 43.4%. The positive number of protein chip antibodies in ~ (14) C-UBT positive patients was 38, the positive rate was 38%. The positive rate of C-UBT was (14) C-UBT positive in 36 cases (46.7%) in the protein chip antibody-positive patients. Conclusion The positive rates of protein chip antibody and ~ (14) C breath test in this group are lower than the average infection rate of H. pylori in China, indicating that the sensitivity of the above two methods for diagnosis of Hp infection needs to be improved.