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目的 :评价泛昔洛韦在复发性生殖器疱疹治疗中的疗效和不良反应。方法 :5 8例复发性生殖器疱疹随机分成两组 ,一组用泛昔洛韦片 2 5 0mg ,每日 3次 ,连续 7d。另一组用阿昔洛韦片 2 0 0mg ,每日 5次 ,连续 7d。结果 :两组痊愈率分别为 86 .7%、75 .0 % ,有效率分别为 10 0 %和 96 .4 %。用泛昔洛韦痊愈时间为 (4 7± 1 8)d ,阿昔洛韦为 (5 2± 1 1)d(P <0 0 5 )。结论 :泛昔洛韦治疗生殖器疱疹具有用药剂量小、次数少、起效快、痊愈时间短的特点 ,可作为治疗生殖器疱疹的首选药物
Objective: To evaluate the efficacy and side effects of famciclovir in the treatment of recurrent genital herpes. Methods: Fifty-eight recurrent genital herpes were randomly divided into two groups. One group was treated with famciclovir 250 mg three times daily for 7 days. The other group with acyclovir film 200 mg 5 times a day for 7 days. Results: The cure rates of the two groups were 86.7% and 75.0% respectively, and the effective rates were 100% and 96.4% respectively. Treatment with famciclovir was (47 ± 18) days for acyclovir and (52 ± 11) days for acyclovir (P <0.05). Conclusion: Famciclovir treatment of genital herpes with a small dose, the frequency of less, fast onset, short recovery time can be used as the treatment of genital herpes drug of choice