论文部分内容阅读
近20余年来,急性白血病(急白)的治疗已取得重大进展,这主要是由于新化疗药物的开发、化疗方法的改进、支持疗法的加强以及骨髓移植的开展。目前国内仍以化疗为治疗急白的主要手段,但各单位所采取的方案虽类似而效果却有相当大的差距。现将提高急白疗效的一些粗浅体会介绍如下。 1 急白的诱导缓解治疗治疗必须及时,选用恰当的药物、剂量和疗程也必须合适。延缓治疗会使病人体内瘤负荷过大,只有及时并采用适当、足够剂量的化疗药物,务使病人在第一或第二个疗程就达到完全缓解(CR),才有可能使病人达到长期存活。 1.1及时诊断才能及时治疗急白的诊断不难,但如症状不典型、血象变化不显著或由于化验人
In the past 20 years, significant progress has been made in the treatment of acute leukemia (acute whiteness) mainly due to the development of new chemotherapeutic drugs, the improvement of chemotherapy methods, the enhancement of supportive therapies and the development of bone marrow transplantation. At present, chemotherapy is still the primary means of treating acute and white diseases. However, although the schemes adopted by various units are similar and the results are quite different, there is a considerable gap. Now some of the superficial experience to improve the effectiveness of acute white described below. 1 acute white induction therapy must be promptly treated, the appropriate choice of drugs, dosage and treatment must also be appropriate. Prolonged treatment of patients with tumor load will be too large, only the timely and appropriate dose of chemotherapy drugs, so that patients in the first or second course of treatment to achieve complete remission (CR), only the possibility of long-term survival of patients . 1.1 timely diagnosis in time for the diagnosis of acute white is not difficult, but if the symptoms are not typical, no significant change in blood or due to laboratory personnel