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DFS有5-羟色胺样活性,动物实验证明具有镇静作用。它对小鼠还有抗麻风作用,急性慢性的毒性都很小。在确定抗人麻风作用的试验中,6例印度藉急性瘤型麻风患者,既往未曾治疗过,现在接受每天口服10mgDFS,至少治疗6个月。随机尿检以确保过去未曾用过氨苯砜,并通过测定证实DFS药片中不含异烟肼。除1例治疗约一周后中断外,其余均完成了整个疗程。全部患者都改善了临床症状,其中1例轻度改善,另一例有显著改善,包括皮肤红斑消失、浸润减轻、结节变平。1例因神经炎发作加用了皮质类固醇和手术减压
DFS has serotonin-like activity, animal experiments proved to have a sedative effect. It has anti-leprosy effect on mice, acute and chronic toxicity are very small. In an experiment to determine the anti-human leprosy effect, 6 patients with acute lepromatous leprosy in India, who had never been treated before, now receive oral 10 mg DFS daily for at least 6 months. Random urine tests were performed to ensure that dapsone was not used in the past, and no isoniazid was confirmed in the DFS tablets. In addition to one case of treatment about a week after the interruption, the rest have completed the entire course of treatment. All patients improved clinical symptoms, one of them mildly improved and the other significantly improved, including the disappearance of the skin erythema, the reduction of infiltration and the flattening of the nodules. 1 case of neuritis caused by the addition of corticosteroids and surgical decompression