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目的探讨中西医结合的早期干预模式对提高极低出生体重早产儿生命质量的临床疗效。方法研究开始后连续收录的极低出生体重早产儿120例随机分为两组,干预组进行中西医结合早期干预,观察组进行常规系统保健指导,选择第2、4、6、9、12、18、24个月最后一周为观测周,在观测周内选择实际生长水平、神经、心理、运动等作为生命质量水平的评价指标。结果 1干预组身长、体重的发育优于观察组,有显著差异(P<0.05),两组头围发育无显著差异(P>0.05);2干预组的神经运动检查在视听反应、肌张力、反射、姿势,运动的异常项目明显少于观察组。3《0-6岁儿童神经心理发育》测评结果在干预组2月龄患儿智能发育与观察组相比,无显著性差异。干预组4、6、8、12、18月龄患儿智能发育均优于观察组(P<0.05)。结论中西医结合早期综合干预可以提高患儿的实际生长发育水平,有效地减少神经运动反射异常,提高运动与智能发育水平,提高极低早产儿的生命质量,减低脑瘫发生率。
Objective To explore the clinical efficacy of early intervention mode combining traditional Chinese and western medicine on improving the quality of life of very low birth weight preterm infants. Methods 120 cases of very low birth weight preterm infants consecutively included in the study were randomly divided into two groups. The intervention group received early intervention with integrated traditional Chinese and western medicine. The general health guidance was given to the observation group and the first, second, fourth, sixth, ninth, 18,24 months last week for the observation week, select the actual growth during the observation week, neurological, psychological, exercise as the quality of life evaluation index. Results 1 The body length and body weight of the intervention group were significantly better than those of the observation group (P <0.05). There was no significant difference between the two groups in head circumference development (P> 0.05) The items of reflex, posture and movement were significantly less than those of the observation group. 3 “0-6-year-old children neuropsychological development” test results in the intervention group 2-month-old children with intelligent development compared with the observation group, no significant difference. The intelligence development of the intervention group at 4, 6, 8, 12 and 18 months was better than that of the observation group (P <0.05). Conclusion Integrated early intervention with traditional Chinese and western medicine can improve the actual growth and development of children, reduce abnormal reflexes effectively, increase the level of motor and intelligence development, improve the quality of life in very low preterm infants and reduce the incidence of cerebral palsy.