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在无缺铁,地中海贫血以及细胞毒药物治疗的情况下,平均细胞体积(MCV)正常的巨幼红细胞性贫血极为罕见,以至于血液学工作者甚至不愿意测定血清维生素B_(12)和叶酸的含量,除非患者MCV增高。作者在布林冒斯6个月内发现了3例这样的病人例1:女性,24岁,上腹疼痛、腹泻、体重减轻、闭经和疲乏无力6个月。患者外观苍白,血红蛋白降低,但MCV正常。血片上可见大小不等的红细胞及异形小红细胞,但没有分叶过多的多形核粒细胞。骨髓主要是巨幼红细胞,储存铁增加。空肠活检见粘膜扁平。诊断麦胶性肠病(非热带性斯泼鲁),用维生素B_(12),叶酸和不含麦胶
In the absence of iron deficiency, thalassemia and cytotoxic drug therapy, megaloblastic anemia with normal mean cell volume (MCV) is extremely rare, and even hematologists are not even willing to measure serum vitamin B 12 and folic acid Content, unless the patient MCV increased. The authors found 3 such patients within 6 months of Bryan’s erection Example 1: Female, 24 years old, with abdominal pain, diarrhea, weight loss, amenorrhoea, and fatigue for 6 months. Patients pale appearance, hemoglobin decreased, but MCV normal. Red blood cells ranging from red blood cells and irregular small red blood cells seen on the blood film, but no lobular pleiotropic polymorphonuclear neutrophils. The bone marrow is mainly melatonin, iron storage increased. Jejunum biopsy see mucosal flat. Diagnosis of wheat gluten enteropathy (non tropical tropho), with vitamin B_ (12), folic acid and non-gummy