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本文介绍46例恶性肿瘤患者实施冻存胎儿胸腺移植前后的 E 玫瑰花形成细胞(E-RFC)水平的变化。移植后较移植前 E-RFC 水平升高(p<0.05)。根据移植前 E-RFC 水平,我们将46例患者分为3组:第1组,E-RFC 水平在40%以下者(7例);第2组,E-RFC 水平在41%～60%之间者(24例),第3组,E-RFC 水平在61%以上者(15例)。移植后各组 E-RFC 水平较移植前平均升高值分别为:22.2%(p<0.01)、7%(p<0.01)、-5.1%(0.2>p>0.1)。从结果看出,通过冻存胎儿胸腺移植可以提高恶性肿瘤患者的E-RFC 水平,特别是 E-RFC 水平在60%以下者。E-RFC 水平在61%以上者实施冻存胎儿胸腺移植无提高 E-RFC 水平作用。
This article describes the 46 cases of malignant tumor patients with frozen fetal thymus before and after the change of E-RFC level. The level of E-RFC before transplantation was higher than that before transplantation (p <0.05). According to pre-transplant E-RFC, 46 patients were divided into 3 groups: group 1, E-RFC level below 40% (7 cases); group 2, E-RFC level 41% to 60% (24 cases), group 3, E-RFC level was above 61% (15 cases). The mean increase of E-RFC in all groups after transplantation was 22.2% (p <0.01), 7% (p <0.01), and 5.1% (0.2> p> 0.1) respectively. From the results, it can be seen that the E-RFC level of malignant tumor patients can be improved by cryopreservation of thymus in fetus, especially when the E-RFC level is below 60%. E-RFC level of 61% or more in the implementation of frozen fetal thymus transplantation did not improve the role of E-RFC level.