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目的探讨非胰岛素依赖性糖尿病患者(NIDDM)血清中微量元素与血糖关系。方法分析了80例NIDDM患者以及80例健康体检者的资料,观察患者血清中微量元素与血糖之间的关系。结果 NIDDM患者血清Zn、Se、Cr含量均显著低于健康对照组(P<0.05),血清Cu含量显著高于健康对照组(P<0.05),而2组Mn、Cd、Fe、Pb、Ni、Co、Li及Cu/Zn比相比,差异无统计学意义(P>0.05);血清Zn与血糖呈较弱的负相关性,Cu与血糖之间呈正相关性(P<0.05)。结论纠正NIDDM患者体内存在着的微量元素代谢紊乱,对于糖尿病的临床治疗具有十分重要的意义。
Objective To investigate the relationship between serum trace elements and serum glucose in non-insulin dependent diabetes mellitus (NIDDM). Methods The data of 80 patients with NIDDM and 80 healthy subjects were analyzed and the relationship between serum trace elements and blood sugar was observed. Results The levels of serum Zn, Se and Cr in NIDDM patients were significantly lower than those in healthy controls (P <0.05), and the contents of Cu in serum were significantly higher than those in healthy controls (P <0.05) , Co, Li and Cu / Zn ratio (P> 0.05). There was a weak negative correlation between serum Zn and blood glucose and a positive correlation between Cu and blood glucose (P <0.05). Conclusion It is very important for the clinical treatment of diabetes to correct the metabolic disorder of trace elements in NIDDM patients.