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目的观察普罗帕酮联合稳心颗粒治疗室性期前收缩的疗效及安全性。方法选取室性期前收缩患者144例,随机分为治疗组72例,对照组72例。对照组:口服普罗帕酮150 mg,3次/d。治疗组:在对照组基础上加服稳心颗粒9 g,3次/d。治疗4周为1个疗程,两组患者治疗前后行常规心电图和24 h动态心电图及血尿常规、肝、肾功能检查。结果两组均可显著减少室性期前收缩的发生。两组临床疗效差异有统计意义(P<0.05)。结论普罗帕酮联合稳心颗粒治疗室性期前收缩的疗效优于单用普罗帕酮,药物依从性好,值得临床推广应用。
Objective To observe the efficacy and safety of propafenone combined with Wenxin Granule in the treatment of premature ventricular contractions. Methods A total of 144 patients with premature ventricular contraction were selected and randomly divided into treatment group (n = 72) and control group (n = 72). Control group: oral propafenone 150 mg, 3 times / d. Treatment group: on the basis of the control group plus service heart particles 9 g, 3 times / d. Treatment for 4 weeks for a course of treatment, two groups of patients before and after treatment routine ECG and 24 h Holter, hematuria, liver and kidney function tests. Results Both groups can significantly reduce the occurrence of ventricular premature contraction. The difference between the two groups was statistically significant (P <0.05). Conclusion The effect of propafenone combined with Wenxin Granule in the treatment of premature ventricular contractions is better than that of propafenone alone. The drug compliance is good and worthy of clinical application.