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环丙沙星具有广谱抗菌作用,用以治疗全身感染性疾病,可口服。在正常条件时,健康人的口服生物利用度为55～85%,略低于其它氟喹诺酮类药物,如氧氟沙星。环丙沙星口服生物利用度欠佳,可能因制剂溶解性差吸收不完全,以及胃肠吸收差和首过效应所致。环丙沙星与丁溴东莨菪碱和胃复安的相互作用表明,环丙沙星在胃肠道上端迅速吸收,但尚缺乏环丙沙星吸收以及可能存在的胃肠消除的详细资料,或其它喹诺酮类药物在人体胃肠道不同部位吸收的研究资料。一种特殊的药物释放装置—高频控释胶
Ciprofloxacin has a broad spectrum antibacterial effect, for the treatment of systemic infectious diseases, can be taken orally. Under normal conditions, oral bioavailability of healthy people is 55-85%, slightly lower than other fluoroquinolones, such as ofloxacin. Ciprofloxacin oral bioavailability is poor, may be due to poor solubility of incomplete absorption of the preparation, and poor gastrointestinal absorption and the first pass effect. The interaction of ciprofloxacin with scopolamine and metoclopidine shows that ciprofloxacin rapidly absorbs at the upper gastrointestinal tract but lacks details of the absorption of ciprofloxacin as well as possible elimination of the gastrointestinal tract or other Quinolone drugs absorbed in different parts of the human gastrointestinal research data. A special drug release device - high frequency release gel