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目的研究健脑软胶囊的最佳成型工艺。方法采用单因素试验法确定健脑软胶囊成型的基质和囊材。以流动性、切断性和沉降体积比为指标,对软胶囊内容物的处方进行筛选。结果以大豆油为基质,内容物配比以每1 000粒软胶囊中加入超临界提取物173 g、浸膏粉171 g、蜂蜡25 g、棕榈油15 g、大豆卵磷脂15 g为最佳,并以明胶-甘油-水(2∶1∶2)为囊材制成软胶囊。结论本工艺稳定,操作简便,对产品大生产有指导意义。
Objective To study the best molding process of Jiannao soft capsule. Methods Single factor test was used to determine the matrix and capsule material of Jiannao soft capsule. Taking the fluidity, cuttability and sedimentation volume ratio as indexes, the prescription of soft capsule contents was screened. Results With soybean oil as the matrix, the contents of the contents were added with 173 g of supercritical fluid extract, 171 g of extract powder, 25 g of beeswax, 15 g of palm oil and 15 g of soybean lecithin per 1 000 capsules. , And gelatin - glycerol - water (2: 1: 2) as a capsule made of soft capsule. Conclusion The process is stable, easy to operate, the product has great guiding significance.