论文部分内容阅读
硫酸苯肼与1-苯基-2,3-二甲基-4-氨基-吡唑酮-5(简称氨基安替比林)为匹拉米洞,安乃近等解热镇痛药的主要中间体,生产上系采用亚硫酸钠与亚硫酸氢钠(部分亚硫酸钠铵)作还原剂,所获还原液经硫酸水解,苛性钠或纯碱中和,副产物主要为硫酸钠,此法的优点为亚硫酸钠(或亚硫酸氢钠)较其它还原剂(如铂或镍催化氢化;锌,铁,硫化钠……等)便宜,在设备,原材料的供应、技术、安全等条件上亦无特殊要求,但缺点由于目前副产物硫酸钠的回收价值不大,污水问题未有妥当的解决办法。
Phenylhydrazine sulfate and 1-phenyl-2,3-dimethyl-4-amino-pyrazolone-5 (referred to as amino antipyrine) for the Pami hole, analgin and other antipyretic analgesics The main intermediate, the production of the Department of sodium sulfite and sodium bisulfite (part of the sodium sulfite) as a reducing agent, the resulting reduction solution by sulfuric acid hydrolysis, caustic soda or soda ash by-product is mainly sodium sulfate, this method has the advantage of Sodium sulfite (or sodium bisulfite) is cheaper than other reducing agents (such as hydrogenation of platinum or nickel; zinc, iron, sodium sulfide, etc.) and there are no special requirements on the conditions of equipment, raw material supply, technology, safety, However, the shortcomings of the current by-product sodium sulfate recovery value is not, the sewage problem is not an appropriate solution.