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[目的]根据我院近20年分化型甲状腺癌(DTC)患者~(131)I治疗规范管理前、后的比较,总结其对患者生活质量的多方改善。[方法]将1996年1月至2005年12月规范管理前共治疗的DTC患者53人次与2006年1月至2015年12月规范管理后我科收住治疗DTC共869人次在各层面的生活质量方面进行对比分析。[结果]角色功能、认知功能、社会功能及总体健康状况规范管理后均有改善,差异有统计学意义(P<0.05),特别是情绪功能改善明显,评分有统计学差异(P<0.01),规范治疗后对失眠、疲倦、便秘等症状改善有意义,差异有统计学意义(P<0.05或P<0.01)。[结论]~(131)I治疗规范管理对DTC患者生活质量的改善有肯定意义。
[Objective] To summarize the multifactorial improvement of patients’ quality of life based on the comparison of 131 I treatment standard management in patients with differentiated thyroid cancer (DTC) in the past 20 years in our hospital. [Methods] From January 1996 to December 2005, 53 patients with pre-treatment DTCs under standardized management and 869 patients receiving treatment DTC after our standardized management from January 2006 to December 2015 were living at all levels Quality comparison analysis. [Result] The function of body, cognitive function, social function and overall health condition were improved after the management of standard, the difference was statistically significant (P <0.05), especially the emotional function improved significantly, the score was statistically significant (P <0.01 ). After treatment, the improvement of symptoms such as insomnia, tiredness and constipation was significant, the difference was statistically significant (P <0.05 or P <0.01). [Conclusion] The management of ~ (131) I treatment has certain significance for improving the quality of life in patients with DTC.