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目的探讨卵巢支持-间质细胞肿瘤的CT表现特点。方法搜集经手术病理证实的8例卵巢支持-间质细胞肿瘤的CT资料,分析其CT表现。结果 8例卵巢支持-间质细胞肿瘤中,7例表现为边界清晰的囊实性或实性肿块,1例呈多房囊性,增强扫描囊壁壁结节明显强化,余7例实性成分有不同程度的强化,明显强化4例,中度强化2例,轻度强化1例。其中5例<30岁,5例睾酮水平持续升高,2例泌乳素水平升高,3例AFP升高,2例CA125升高。免疫组织化学标记物中阳性表达前三位由高到低依次为:Inhibin-α(100%)、Vimentin(75%)、CD56(50%)。结论卵巢支持-间质细胞肿瘤在CT上多呈单侧附件区的实性或囊实性肿块,边界清楚,实性部分多强化明显,且呈进行性强化,结合临床发病年龄、激素水平异常,尤其是血清睾酮水平提高,以及免疫组织化学检查等有助于该病的诊断。
Objective To investigate the CT features of ovarian support-stromal tumor. Methods CT data of 8 cases of ovarian support-stromal tumor confirmed by surgery and pathology were collected and their CT findings were analyzed. Results Of the 8 cases of ovarian support-stromal cell tumor, 7 cases showed cystic solid or solid mass with clear boundary, 1 case showed multi-atrial cyst, enhanced the enhancement of cyst wall nodules, The ingredients have different degrees of enhancement, significantly enhanced in 4 cases, moderate enhancement in 2 cases, mild enhancement in 1 case. Among them, 5 cases were <30 years old, 5 cases of testosterone levels continued to rise, 2 cases of prolactin levels increased, 3 cases of AFP increased, 2 cases of CA125 increased. Immunohistochemical markers in the top three positive to descending order were: Inhibin-α (100%), Vimentin (75%), CD56 (50%). Conclusions Ovarian supportive mesenchymal tumors mostly show solid or cystic mass on CT, with clear boundary and solid part. The solid part of the ovarian support-interstitial tumor is strengthened obviously. Combined with clinical age of onset and abnormal hormone level , Especially serum testosterone levels, and immunohistochemistry to help diagnose the disease.