Safety,immunogenicity,and cross-species protection of a plasmid DNA encoding Plasmodium falciparum S

• 作 者: Nyamongo Onkoba Ruth M.Mumo Ho
• 机 构: DepartmentofTropical&,InfectiousDiseases,SchoolofBiologicalSciences,DepartmentofBiochemistry,Kiri
• 出 处: 生物医学研究杂志：英文版
• 发表日期: 2017年4期
• 关键词: 恶性疟原虫 质粒DNA 免疫原性 抗原表位 趋化因子 保护作用 安全性 物种 malaria DNA vaccines serine repeat antige
• 基金项目: Gene Art for engineering the vaccine constructs and the Uganda Council of Science and Technology （UCST）/World Bank for providing the funds for the work

Incorporation of biomolecular epitopes to malarial antigens should be explored in the development of straintranscending malarial vaccines.The present study sought to determine safety,immunogenicity and cross-species efficacy of Plasmodium falciparum serin