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目的：了解胃粘膜淋巴滤泡的发生与Ｈｐ感染的关系、胃炎活动程度对其发生的影响以及它在Ｈｐ相关性胃十二指肠疾病中的存在状况。方法：本文对６５５例慢性胃、消化性溃疡的患者进行胃镜检查，取粘膜组织作幽门螺杆菌（Ｈｐ）检测和组织病理观察。结果：在Ｈｐ感染的患者中胃粘膜淋巴滤泡的检出率为６０１％，而无Ｈｐ感染者仅为１７１％；Ｈｐ感染者中，胃窦部粘膜淋巴滤泡的发生率（５１１％）明显高于胃体部粘膜（１９３％）；活动性胃炎中胃粘膜淋巴滤泡的发生率高于非活动性胃炎；在Ｈｐ相关性慢性胃炎、十二指肠球溃和胃溃疡中淋巴滤泡的发生率无明显差异。结论：胃粘膜淋巴滤泡的发生与Ｈｐ感染可能有直接的关系，可作为Ｈｐ相关性胃十二指肠疾病中一个较为恒定的形态学特征和标志
Objective: To investigate the relationship between the occurrence of gastric mucosal lymphoid follicles and Hp infection, the effect of gastritis activity on its occurrence and its existence in Hp-related gastroduodenal diseases. Methods: In this paper, 655 patients with chronic gastric and peptic ulcer were examined by gastroscopy. The mucosa was taken for examination of Helicobacter pylori (Hp) and histopathological observation. Results: The detection rate of gastric mucosal lymphoid follicles in patients with Hp infection was 60.1%, but only 17.1% without Hp infection. The incidence of gastric mucosal lymphoid follicles in Hp infected patients (511%) was significantly higher than that of gastric mucosa (193%). The incidence of gastric mucosal lymphoid follicles in active gastritis was higher than that in inactive gastritis. In Hp-related chronic gastritis, duodenal There was no significant difference in the incidence of lymphoid follicles between ulcer and gastric ulcer. Conclusions: The occurrence of gastric mucosal lymphoid follicles may be directly related to Hp infection and may be used as a more constant morphological characteristic and marker in Hp-related gastroduodenal diseases