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目的探讨强化护理干预对骨肿瘤患者不良反应和下肢功能的影响。方法选取2014年8月至2016年8月河北省沧州市中心医院收治的90例骨肿瘤患者,采用随机数表法分为对照组与观察组,每组45例,观察组患者在常规护理基础上给予强化护理,对照组患者给予常规护理,对比两组患者的不良反应、负性情绪和下肢功能。结果对照组患者骨髓抑制、口腔黏膜炎、肝肾功能损害、胃肠道反应、肌肉关节痛和过敏反应的发生率分别为17.8%、20.0%、22.2%、31.1%、17.8%和13.3%,观察组患者上述指标分别为11.1%、11.1%、13.3%、17.8%、8.9%和6.7%,观察组患者上述指标发生率均较低,组间比较差异均有统计学意义(均P<0.05)。治疗后,对照组患者的焦虑自评量表(SAS)和抑郁自评量表(SDS)评分分别为(53.02±5.19)分和(52.89±5.19)分,观察组患者的SAS及SDS评分分别为(46.56±5.23)分和(45.71±5.16)分,两组患者护理后与护理前相比,上述评分均降低,护理后观察组患者上述评分比对照组低,差异均有统计学意义(均P<0.05)。对照组患者护理3周时下肢功能为(23.78±2.45)分,护理5周时下肢功能为(17.56±2.56)分,观察组患者上述评分分别为(15.36±2.19)分和(8.93±2.41)分,两组护理3周和护理5周下肢功能评分与护理前相比较低,观察组患者上述评分比对照组患者低,差异均有统计学意义(均P<0.05)。结论强化护理干预可有效减少骨肿瘤患者化疗期间的不良反应,缓解负性情绪,促进患者下肢功能恢复。
Objective To investigate the effects of intensive nursing intervention on adverse reactions and lower extremity function in patients with bone cancer. Methods Ninety patients with bone tumors who were admitted to Cangzhou Central Hospital from August 2014 to August 2016 were randomly divided into control group and observation group with 45 cases in each group. The patients in observation group were divided into control group On the intensive care, patients in the control group were given routine care, adverse reactions, negative emotions and lower limb function were compared between the two groups. Results The incidences of myelosuppression, oral mucositis, liver and kidney dysfunction, gastrointestinal tract reaction, muscular joint pain and anaphylaxis in the control group were 17.8%, 20.0%, 22.2%, 31.1%, 17.8% and 13.3%, respectively. The above indexes in the observation group were 11.1%, 11.1%, 13.3%, 17.8%, 8.9% and 6.7%, respectively. The incidence of the above indexes in the observation group was lower and the difference between the two groups was statistically significant (P <0.05 ). After treatment, the SAS and SDS scores in the control group were (53.02 ± 5.19) and (52.89 ± 5.19), respectively. SAS and SDS scores in the observation group were respectively (46.56 ± 5.23) points and (45.71 ± 5.16) points respectively. After the nursing, the scores of the two groups were lower than those before the nursing, and the scores of the above observation group were lower than those of the control group after nursing All P <0.05). In the control group, the function of the lower limbs was (23.78 ± 2.45) at 3 weeks and that of the lower limbs was (17.56 ± 2.56) at 5 weeks of care. The scores in the observation group were (15.36 ± 2.19) and (8.93 ± 2.41) The scores of lower extremity function in three groups of nursing and five weeks of nursing were lower than those in the control group. The scores in the observation group were lower than those in the control group (all P <0.05). Conclusion Intensive nursing intervention can effectively reduce adverse reactions during chemotherapy in patients with bone cancer, relieve negative emotions, and promote the recovery of lower extremity function in patients.