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脂肪肝是多种原因引起的肝细胞内脂质过多蓄积的代谢性肝病。脂质是指脂肪(甘油三酯和游离脂肪酸)和类脂(磷脂、胆固醇、胆固醇醋、类固醇、糖脂等)。当肝内脂质含量超过肝脏湿重的5%,或显微镜下肝组织切片每单位面积有1/3以上的肝细胞见脂肪滴存在时,称为脂肪肝。轻者为单纯性脂肪肝;在脂肪变性的基础上引起肝细胞坏死和炎症反应则为脂肪性肝炎;进而引起肝纤维化则为脂肪性肝纤维化;再发展引起肝小叶纤维间隔并假小叶形成则为肝硬化。目前,将上述3种脂肪肝发展的疾病谱统称为脂肪性肝病。
Fatty liver is a variety of causes caused by excessive accumulation of lipid in liver cells metabolic liver disease. Lipids refer to fats (triglycerides and free fatty acids) and lipids (phospholipids, cholesterol, cholesterol esters, steroids, glycolipids, etc.). When the intrahepatic lipid content of more than 5% of the liver wet weight, or liver tissue sections per unit area under the microscope more than 1/3 of liver cells see the presence of fat droplets, known as fatty liver. The light of simple fatty liver; on the basis of steatosis caused by necrosis of liver cells and inflammatory response is steatohepatitis; then cause liver fibrosis compared with fatty liver fibrosis; re-development of the hepatic lobule fibrillation and false leaflets The formation of cirrhosis. Currently, the above three kinds of fatty liver disease spectrum are collectively referred to as fatty liver disease.