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来自于美国scripps研究所的研究人员现已鉴别出一种小分子化合物,该化合物能够诱导细胞进行逆分化,从现有的细胞状态逆分化成原来的前体细胞。这种被称为“逆转素”的小分子化合物能够使按正常程序分化的肌肉细胞进行逆转化,重新回到前体细胞阶段。这些前体细胞具有多向分化能力,可分化成不同类型的细胞。因此,逆转素可用于成熟细胞无限逆转化成为前体细胞的有效工具,从而使一
Researchers from the U.S. scripps Institute have now identified a small molecule compound that induces cells to undergo dedifferentiation, de-differentiating from their current cellular state into their own precursor cells. This small molecule known as “retrograde factor” reverses the normal differentiation of muscle cells back to the precursor cell stage. These precursor cells have a multi-directional ability to differentiate into different types of cells. Thus, retrotensin can be used as an efficient tool for the infinite retrotransformation of mature cells into progenitor cells, so that one