【摘 要】
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Alzheimer\'s disease (AD),also known as Alzheimer\'s,is a chronic neurodegenerative disorder with hallmark amyloid plaques in brain tissue.The diseases commences slowly and worsens over time (Sjogren et al.1952).Although it has been investigated for o
【机 构】
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MOE & MOH Key Laboratory of Medical Molecular Virology, School of Basic Medicine, Shanghai Medical C
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Alzheimer\'s disease (AD),also known as Alzheimer\'s,is a chronic neurodegenerative disorder with hallmark amyloid plaques in brain tissue.The diseases commences slowly and worsens over time (Sjogren et al.1952).Although it has been investigated for over six decades,the cause of AD is still not completely understood.It was initially thought to be caused by genetic heritability (autosomal mutation leading to aggregation of β-amyloid and misfolded tau proteins) or head injury.
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