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目的探讨胃肠道间质瘤的诊断、治疗方法。方法回顾分析2002-2009年收治的28例胃肠道间质瘤(GIST)的临床资料。结果本组平均年龄56岁,全部病例均行手术治疗,病理检查证实为胃肠道间质瘤。术后随访2例局部复发再次来院手术,1例术后13个月广泛转移死亡。1例因急性心肌梗死于术后2 a死亡。结论 GIST的诊断有赖于内镜及影像学检查相结合。手术切除是有效治疗手段。手术操作应遵循无瘤操作及防止瘤体破溃原则。
Objective To investigate the diagnosis and treatment of gastrointestinal stromal tumors. Methods The clinical data of 28 cases of gastrointestinal stromal tumors (GIST) admitted from 2002 to 2009 were retrospectively analyzed. Results The average age of 56 patients in this group, all cases underwent surgical treatment, pathological examination confirmed gastrointestinal stromal tumors. Follow-up 2 cases of local recurrence and hospitalization again, 1 case of extensive metastasis after 13 months of death. One case died of acute myocardial infarction 2 years after operation. Conclusion The diagnosis of GIST depends on the combination of endoscopy and imaging. Surgical resection is an effective treatment. Surgical procedures should follow the principle of tumor-free operation and ulceration prevention.