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小檗碱(berberine,Ber,黄连素)是从黄连、黄柏、南天竹、三颗针等植物中提取的异喹啉生物碱,药用其盐酸盐。现就近年来报道的小檗碱对心血管系统的作用及临床应用综述如下:1 正性肌力作用 小檗碱在一定剂量时具有正性肌力作用,且对心肌收缩力的影响具有小剂量增强.大剂量抑制的双相特征。通过冠状动脉注入微粒造成急性左心衰
Berberine (Berberine, Ber, Berberine) is an isoquinoline alkaloid extracted from the plants of Coptis chinensis, Cortex phellodendri, Nandina, three needles and other medicinal hydrochloride. Now reported in recent years, the role of berberine on cardiovascular system and clinical application are summarized as follows: 1 positive inotropic effect Berberine in a certain dose with positive inotropic effect, and myocardial contractility with a small dose Enhanced biphasic characteristics of high-dose inhibition. Acute left heart failure caused by particles injected through the coronary arteries