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Aim: The present project is to seek the possible electrical stimulation parameter by which wind-up of withdrawal reflex of rats and set up a appropriate animal model for recording the withdrawal reflex of wind-up phenomenon. Meanwhile, a parallel comparison will be made between the recording of withdrawal reflex and dorsal horn (DH) neuron responses in order to investigate the possible correlation associated with sensory and motor interaction of pain information via simultaneous recording. On the other hand, another comparison study
Aim: The present project is to seek the possible electrical stimulation parameter by which wind-up of withdrawal reflex of rats and set up an appropriate animal model for recording the withdrawal reflex of wind-up phenomenon. Meanwhile, a parallel comparison will be made between the recording of withdrawal reflex and dorsal horn (DH) neuron responses in order to investigate the possible correlation associated with sensory and motor interaction of pain information via simultaneous recording. On the other hand, another comparison study