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目的比较常规磁共振(MRI)检查和快速液体衰减翻转恢复序列(FLAIR)技术对颅脑多发性硬化症(MS)的诊断价值。方法采用美国GE公司生产的Signa 1.5T Twin Speed磁共振机,对58例经临床与实验室检查明确的MS病例(男34例、女24例,平均年龄35.95岁);例行T1FLAIR、T2WI及FLAIR技术检查,并对所检病灶进行对比。结果(1)FLAIR成像技术共检出病灶877个,T1FLAIR捡出病灶651个,为FLAIR序列总数的74%;T2加权成像检出病灶776个,为FLAIR序列总数的88%;对脑室周围及皮髓交界处病灶的检出率FLAIR序列明显优于T1FLAIR及T2WI。(2)MS病灶主要分布在脑室周围白质和半卵元中心区,两处病灶占总病灶数的96.1%。(3)病灶形态多为斑片状、圆形及/或卵圆形,也有少部分可见大片状病灶,甚至有的表现为假瘤样病灶。病灶的直径多小于1.5 cm。结论FLAIR序列对诊断MS优于T1FLAIR、T2WI,其发现MS病灶明显多于后者,且重复性好,能较好的显示近皮层处和脑室旁等传统T2易漏诊病灶,尤其对小病灶显示情况明显优于T1FLAIR、T2WI。
Objective To compare the diagnostic value of conventional magnetic resonance imaging (MRI) and rapid fluid decay reversal recovery sequence (FLAIR) in multiple sclerosis of the brain (MS). Methods Fifty-eight MS patients (34 males and 24 females, with an average age of 35.95 years) with definite clinical and laboratory tests were diagnosed by Signa 1.5T Twin Speed Magnetic Resonance Imaging Machine manufactured by GE Company. The routine T1FLAIR, T2WI and FLAIR technical examination, and the lesion were compared. Results (1) A total of 877 lesions were detected by FLAIR imaging, 651 were detected by T1FLAIR, accounting for 74% of the total number of FLAIR sequences and 776 by T2 weighted imaging, accounting for 88% of the total number of FLAIR sequences. The detection rate of lesions at the junction of the spinal cord FLAIR sequence was significantly better than T1FLAIR and T2WI. (2) MS lesions were mainly distributed in the periventricular white matter and semi-oval central area, the two lesions accounted for 96.1% of the total number of lesions. (3) Most of the lesions were patchy, round and / or oval, with a small number of visible large flaky lesions and some even pseudotumor-like lesions. The lesion diameter less than 1.5 cm. Conclusion The FLAIR sequence is superior to T1FLAIR and T2WI in diagnosing MS, and it is found that MS lesions are much more than the latter in FLAIR sequence, and the repeatability is good. FLAIR sequences can show the lesions easily missed by traditional T2, especially near the cortex and ventricle, especially for small lesions The situation is clearly superior to T1FLAIR, T2WI.