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目的比较雷尼替丁、泮托拉唑分别与抗生素联合治疗胃溃疡的临床效果。方法选择2012年4月-2014年4月收治的胃溃疡患者88例,随机分为观察组和对照组各44例,对照组行雷尼替丁联合克拉霉素及阿莫西林治疗,观察组采取泮托拉唑联合克拉霉素及阿莫西林治疗,对2组患者治疗后临床疗效进行观察。结果观察组治疗总有效率为93.18%明显高于对照组的70.45%(P<0.05);观察组症状及体征消失时间均短于对照组,不良反应发生率低于对照组,差异均有统计学意义(P<0.05)。结论胃溃疡采取泮托拉唑与抗生素治疗,安全性高,可快速缓解症状及体征,提高临床疗效,值得临床推广使用。
Objective To compare the clinical effects of ranitidine and pantoprazole with antibiotics in the treatment of gastric ulcer. Methods Eighty-eight patients with gastric ulcer admitted from April 2012 to April 2014 were randomly divided into observation group (44 cases) and control group (n = 44). The control group received ranitidine combined with clarithromycin and amoxicillin, and the observation group To take pantoprazole combined with clarithromycin and amoxicillin treatment, the clinical efficacy of two groups of patients were observed after treatment. Results The total effective rate of the observation group was 93.18%, which was significantly higher than that of the control group (70.45%, P <0.05). The symptom and signs disappeared in the observation group and the incidence of adverse reactions was lower than that in the control group Significance (P <0.05). Conclusion The treatment of gastric ulcer with pantoprazole and antibiotics is safe and can relieve the symptoms and signs quickly and improve the clinical curative effect. It is worth to be used clinically.