Copper Ions Stimulate the Proliferation of Hepatic Stellate Cells via Oxygen Stress in vitro

• 作 者: 徐三清 朱慧云 林剑国 苏堂枫 刘艳 罗小平
• 机 构: DepartmentofPediatrics,DepartmentofInternalMedicine
• 出 处: Journal of Huazhong University of Science and Technology(Med
• 发表日期: 2013年1期
• 关键词: 脂质过氧化物 细胞增殖 肝星状细胞 体外培养 铜离子 应激刺激 还原型谷胱甘肽 N-乙酰半胱氨酸 copper ions hepatic stellate c

This study examined the effect of copper ions on the proliferation of hepatic stellate cells (HSCs) and the role of oxidative stress in this process in order to gain insight into the mechanism of hepatic fibrosis in Wilson’s disease. LX-2 cells, a cell li