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目的:研究肾细胞癌淋巴结转移的危险因素,并建立Logistic回归模型。方法:2002年2月～2010年10月我院手术治疗的肾细胞癌163例,对其临床病理资料进行单因素和多因素的Logistic回归分析。结果:淋巴结转移的发生率为20.9%(34/163)。单因素分析显示:肿瘤大小、临床分期、Fuhrman核分级和贫血与肾细胞癌淋巴结转移的风险有关(P<0.05);多因素分析显示:肿瘤大小、临床分期和Fuhrman核分级是RCC淋巴结转移独立的风险因素。结论:肾细胞癌淋巴结转移的风险与肿瘤大小、临床分期和Fuhrman核分级有关,Logistic回归模型对于判断预后、指导术后治疗及随访方案的制订具有重要作用。
Objective: To study the risk factors of lymph node metastasis in renal cell carcinoma and establish Logistic regression model. Methods: From February 2002 to October 2010, 163 cases of renal cell carcinoma underwent surgical treatment in our hospital. One-factor and multi-factor logistic regression analysis was performed on the clinical and pathological data. Results: The incidence of lymph node metastasis was 20.9% (34/163). Univariate analysis showed that the tumor size, clinical stage, Fuhrman nuclear grade and anemia were associated with the risk of lymph node metastasis of renal cell carcinoma (P <0.05). Multivariate analysis showed that tumor size, clinical stage and Fuhrman nuclear grade were independent of RCC lymph node metastasis Risk factors. Conclusion: The risk of lymph node metastasis of renal cell carcinoma is related to tumor size, clinical stage and Fuhrman nuclear classification. Logistic regression model plays an important role in prognosis, postoperative treatment and follow-up planning.