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目的 :评价 1 5 3S- DTMP治疗恶性转移瘤的疗效。方法 :对 113例原发性恶性肿瘤骨转移瘤患者进行 1 5 3Sm-EDTMP治疗。结果 :(1)镇痛方面 ;第一次治疗有效率为 6 1% (6 9/ 113) ;第二次治疗有效率为 6 6 % (74/ 92 ) ;第三次治疗有效率为 88.3% (5 3/ 6 0 )。 (2 )骨显像方面 ,经 1 5 3Sm- EDTMP2 - 6次治疗后 ,患者原骨转移灶确有减淡或消失改变。结论 :研究结果表明 ,1 5 3Sm- EDTMP作为一种内照射治疗药物 ,对恶性骨转移瘤是安全有效的 ,特别适合门诊病人的治疗。
Objective: To evaluate the efficacy of 1 5 3S-DTMP in the treatment of malignant metastases. Methods: One hundred and thirty-three patients with primary malignant tumors were treated with 153Sm-EDTMP. Results: (1) In terms of analgesia, the effective rate for the first treatment was 6 1% (6 9/ 113); the effective rate for the second treatment was 6 6% (74/ 92); the effective rate for the third treatment was 88.3 % (5 3/6 0 ). (2) Bone imaging, after 153-Sm-EDTMP2 - 6 treatments, the patient’s original bone metastasis did not change or disappear. Conclusion: The results of the study showed that 153Sm-EDTMP, as an internal radiation therapy drug, is safe and effective for malignant bone metastases, and is particularly suitable for the treatment of outpatients.