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对160例住院重症肺炎病儿进行了急性期与恢复期痰液SIgA 含量检测,并与115例健康小儿的局部和全身免疫状态进行对照。急性期肺炎病儿痰SIgA 含量均有不同程度增加,其中呼吸道合胞病毒肺炎、葡萄球菌肺炎、阴性杆菌肺炎SIgA 含量与恢复期比较,P 值均<0.05,有显著性差异。提示由于抗原的刺激,局部SIgA分泌量增加,有利于阻止病毒和细茵在粘膜表面繁殖。3岁以上肺炎蛆急性期病儿SIgA 含量与正常同龄儿对照,明显低于对照组,P<0.05。提示3岁以上正常儿,可能SIgA 分泌水平已接近正常成人水平,使两组差异显著。对38例志性期肺炎病儿进行总E 玫瑰花细胞(ET)检测,其中30例明显低于正常对照值,降低范围在5～33%,提示ET 检测作为病毒肺炎细胞免疫功能的一项指标可能有一定参考价值。
The acute and convalescent sputum SIgA levels were measured in 160 hospitalized children with severe pneumonia and compared with the local and systemic immune status of 115 healthy children. Sputum SIgA levels in children with acute pneumonia were increased to varying degrees, including respiratory syncytial virus pneumonia, staphylococcus pneumoniae, negative bacilli SIgA content and recovery period, P values were <0.05, a significant difference. Tip Due to antigen stimulation, local SIgA secretion increased, is conducive to preventing the virus and bacteria in the mucosal surface reproduction. SIgA levels in children with pneumonia and maggots older than 3 years old were significantly lower than those in normal controls (P <0.05). Tip normal children over the age of 3, may SIgA secretion levels close to normal adult levels, the two groups significantly different. Thirty-eight patients with atypical pneumonia were tested for total E rose cells (ET), of which 30 were significantly lower than the normal control, a range of 5 to 33% reduction, suggesting ET detection as a cellular immune function of virus pneumonia Indicators may have some reference value.