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目的 分析腹腔镜胆囊切除联合内镜逆行胆管取石治疗胆囊结石并继发胆总管结石临床效果.方法 采用腹腔镜胆囊切除联合内镜逆行胆管取石治疗观察组患者,采用传统手术方法治疗对照组患者,对比两组手术指标(手术时间、术中出血量、肠鸣音恢复时间)、住院费用和住院时间、并发症(感染、胆漏、组织损伤等)发生率、术后4个月疾病复发情况.结果 与对照组相比,观察组手术时间、术中出血量、肠鸣音恢复时间较低,两组比较差异具有统计学意义(P＜0.05);与对照组相比,观察组住院费用和住院时间较低,两组比较差异具有统计学意义(P＜0.05);观察组并发症发生率(5.88％)低于对照组(27.27％),差异具有统计学意义(x2=5.584,P＜0.05).结论 腹腔镜胆囊切除联合内镜逆行胆管取石治疗胆囊结石并继发胆总管结石可减少术中出血量,降低手术时间,促进患者恢复,减轻患者经济负担,具有较高的推广价值.“,”Objective To analyze the clinical effect of laparoscopic cholecystectomy combined with endoscopic retrograde bile duct stones in the treatment of gallbladder stone and secondary common bile duct stones.Methods Laparoscopic cholecystectomy combined with endoscopic retrograde bile duct stones were used in the observation group,and the patients in the control group were treated with traditional operation method.We compared the two groups of operation index (operation time,intraoperative bleeding,bowel sounds recovery time),hospitalization expenses and hospitalization time,complications (infection,bile leakage,tissue injury) incidence,postoperative four month recurrence of the disease.Results Comparing with the control group,the observation group of operation time,intraoperative blood loss,recovery time of bowel sound was low,the difference between the two groups was statistically significant (P ＜ 0.05);Comparing with the control group,the hospitalization expenses and the length of stay in the observation group were lower,and the difference between the two groups was statistically significant (P ＜ 0.05);The incidence rate of complications in the observation group (5.88％) was lower than that in the control group (27.27％),and the difference was statistically significant (x2 =5.584,P ＜ 0.05).Conclusion Laparoscopic gallbladder resection combined with endoscopic retrograde cholangiopancreatography take stone in the treatment of gallbladder stones and secondary common bile duct stones can reduce the amount of bleeding during the operation,less operation time,promote the recovery of patients,reduce the economic burden of the patients,with high value of popularization.