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大多数人在幼儿及学龄时期已经感染过麻疹,成人发病仅是极个别的。据Ueda等报告,在幼儿或学龄时期患过麻疹的人抗体持续存在,在成人几乎100％保持有抗体。然而,这种抗体究竟是小儿时期患过麻疹的结果,还是后来由于再感染而维持高的抗体水平,为探讨这一问题作者选择横滨市周围人口稠密地区484名65岁以上(男202人、女282人)为对象进行研究。他们以往未接种过麻疹疫苗,大多在幼儿时期受过自然感染,维持较高的抗体水平。对每个人用预防医学研究所麻疹研究室的方法检测血凝抑制抗体(HI)和中和抗体,获得如下结果:
Most people have been infected with measles in early childhood and school age, and adult morbidity is very rare. According to reports by Ueda et al., Human antibodies to measles in young children or school age persist, leaving almost 100% of antibodies in adults. However, whether this antibody was the result of measles in infancy or the subsequent maintenance of high antibody levels due to re-infection, in order to explore this issue, the authors selected 484 people over 65 years old (202 males, Female 282 people) for the study. They have not been vaccinated against measles in the past, most of them were naturally infected during early childhood, maintaining high antibody levels. The hemagglutination inhibition (HI) and neutralizing antibodies were tested for each person using the Institute of Preventive Medicine’s Measles Laboratory and the following results were obtained: