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作者对125例住院和门诊各型原发性肾小球肾炎病人,进行血浆VIII R∶Ag的测定。检查发现,除肾病型恢复期外,其它各型原发性小球性肾炎的VIII R∶Ag都高于正常对照。在肾病综合征时,VIII R∶Ag值与尿蛋白量呈正相关,与血浆白蛋白呈负相关(包括尿毒症、氮质血症)。血浆纤维蛋白升高者,VIII R∶Ag也显著高于正常。结论认为,VIII R∶Ag值的升高,可反映血管内膜的损伤,其升高幅度随肾功能恶化程度而相应增大,有助于估计预后.对VIII R∶Ag升高的机理进行了讨论。
The author of 125 inpatient and outpatient various types of primary glomerulonephritis patients, plasma VIII R: Ag determination. Examination found that in addition to the recovery of kidney disease, the other types of primary glomerulonephritis VIII R: Ag are higher than the normal control. In nephrotic syndrome, the value of VIII R: Ag is positively correlated with urinary protein and negatively correlated with plasma albumin (including uremia, azotemia). Elevated plasma fibrin, VIII R: Ag was also significantly higher than normal. The conclusion is that the increase of VIII R: Ag value can reflect the damage of intima of the intima, and its increasing amplitude increases correspondingly with the worsening of renal function, which is helpful to estimate the prognosis. Discuss.