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目的:探讨普贝生用于足月妊娠引产的临床效果。方法:选择120例孕37~41+6周单胎、头位、无宫缩的初产妇为研究组,使用普贝生(含前列腺E2500 mg)一枚,置入产妇的阴道后旋转90度,横置于后穹窿内,嘱咐产妇卧床30 m in,观察宫颈成熟度,阴道分娩和剖宫产率。同期使用催产素静滴组作为对照组,对照组在500 m l 5%GS中加催产素2.5 u,静脉滴入,每15 m in增加5滴。结果:普贝生组宫颈成熟度高。研究组和对照组的宫颈B ishop评分用药前分别为3.19±1.38和3.21±1.16,无显著性差异(P>0.05),用药后两组评分分别为8.1±1.94和5.2±1.4,存在显著性差异(P<0.05)。研究组总产程为(9.85±2.32)h,对照组为(14.96±3.25)h,两组有显著性差异(P<0.05);产后出血量研究组为(165.3±38.6)m l;对照组为(236.6±39.8)m l,两组有显著性差异(P<0.05);研究组发生新生儿窒息11例(9.17%,11/120),对照组10例(8.33%,10/120),无显著性差异(P>0.05);研究组阴道分娩率高。结论:普贝生用于足月妊娠引产疗效可靠,建议临床推广使用。
Objective: To investigate the clinical effect of pubezheng on induced abortion in full-term pregnancy. Methods: A total of 120 primipara, head position, and uterine contracted primiparae of 37 pregnant women with 37 ~ 41 + 6 weeks of pregnancy were enrolled in this study. One pregnant Phevon (including prostate E2500 mg) , Transverse placed in the posterior fornix, asked maternal ambulation 30 m in, observe the cervical maturity, vaginal delivery and cesarean section rate. In the same period, the oxytocin intravenous infusion group was used as the control group. In the control group, oxytocin 2.5 u was added to 500 mL of 5% GS and dripped intravenously for 5 drops every 15 minutes. Results: Pubei group cervical maturity. The cervical B ishop scores in study group and control group before treatment were 3.19 ± 1.38 and 3.21 ± 1.16, respectively, with no significant difference (P> 0.05). The scores of the two groups after treatment were 8.1 ± 1.94 and 5.2 ± 1.4, respectively Difference (P <0.05). (9.85 ± 2.32) h in the study group and (14.96 ± 3.25) h in the control group, with significant difference between the two groups (P <0.05); the postpartum hemorrhage study group was (165.3 ± 38.6) ml; the control group was (236.6 ± 39.8) ml, there were significant differences between the two groups (P <0.05). There were 11 cases (9.17%, 11/120) in the study group and 10 cases (8.33%, 10/120) Significant difference (P> 0.05); study group, vaginal delivery rate is high. Conclusion: Przewalski’s full-term pregnancy induced labor with reliable efficacy, it is recommended for clinical use.